Physiological Science 136 Exercise and Cardiovascular FunctionCourse Objective: An understanding of the acute and chroniceffects of exercise on cardiac function and the roles that diet andexercise play in preventing and controlling cardiovascular andrelated diseases.Instructor: R. James Barnard, Ph.D. 4303 Life Science Office Hours Wed. 1:30-2:30Required Readings: Selected reprints of current literatureLecture Topics: I. Coronary blood flowautoregulation/neural controldilator reserveO2 supply/demand balanceexercise trainingexercise vs disease hypertrophycollateral developmentII. Peripheral Circulationhypertension – causes and controlperipheral vascular disease – detection andtreatment III. Atherosclerosisstages of developmenttheories on developmentcholesterol metabolismlipoproteins and atherosclerosisdietary regulation of lipoproteinsexercise and lipoproteinsrisk factors for atherosclerosisexercise for preventing atherosclerosisIV. Detection of coronary artery diseasesymptomsstress ECGthallium scanwall motion studyultrafast CTangiogramV. Regression of atherosclerosisperipheral/coronarydrugs vs lifestyleVI. Medical treatment of coronary diseasedrugsangioplastybypass surgeryEECP VII. Insulin resistancecausecontrol by diet and exerciseconsequencesMidterm: 100 points, Feb. 8Final: 150 points, March 15Paper: 50 pointsPapers are due the 8th week on Tues.Papers must include an abstract or summary at thebeginning and a list of references at the end. Give thecomplete reference using a scientific format. The papershould focus on mechanisms when possible as opposed to asummary of