Slide 1Slide 2Slide 3Slide 4Slide 5Slide 6Slide 7Slide 8Slide 9Slide 10Slide 11Slide 12Slide 13Slide 14Slide 15Slide 16Slide 17Slide 18Slide 19Slide 20Slide 21Slide 22Slide 23Slide 24Slide 25Slide 26Slide 27Slide 28Slide 29Slide 30Slide 31Slide 32Slide 33Slide 34473 gpE2 Regrade05100510152025303539MorScoreFrequencyFrequencyAverage = 27.8Standard Deviation = 7.6Affinity constants and Roles of Co-receptors in TCR binding.Summary of the HIV/AIDS epidemic, December 2001. People infected with HIV in 2001 Total 5 Million Adults 4.3 Million Women 1.8 Million Children 15 years 800,000 No. of people living with HIV/AIDS Total 40 Million Adults 37.2 Million Women 17.6 Million Children <15 years 2.7 MillionAIDS deaths in 2001 Total 3 Million Adults 2.4 MillionWomen 1.1 Million Children <15 years 580,000Total no. of AIDS deaths since the beginning of the epidemic until 2001 Total 21.8 MillionAdults 17.5 MillionWomen 9 MillionChildren <15 years 4.3 Million Total no. of AIDS orphans since the beginning of the epidemic until 2000 Total 13.2 MillionSource: CDC-Today, 42 million people are estimated to be living with HIV/AIDS. -An estimated 5 million people acquired HIV. -During 2002, AIDS caused the deaths of an estimated 3.1 million -Women are becoming increasingly affected by HIV. -Approximately 50%, or 19.2 million, are women.Of people with AIDS, 38.6 million are adults, 19.2 million are women, and 3.2 million are children under 15.Exposure Category Male Female Total*Men who have sex with men 368,971 - 368,971Injecting Drug Use 145,750 55,576 201,326Men who have sex with men and inject drugs 51,293 - 51,293Hemophilia/coagulation disorder 5,000 292 5,292Heterosexual contact 32,735 57,396 90,131Recipient of blood transfusion, blood components, or tissue5,057 3,914 8,971Risk not identified 57,220 23,870 81,091* Includes 3 persons whose sex is unknown. US Stats Through December, 2001AIDS StatisticsAs of the end of the June 2001, 793,026 AIDS cases in the USA had been reported to the Centers for Disease Control and Prevention (CDC).Of these, 79% were men, 21% were women and 1% were children less than 13 years of age; 41% were in whites, 41% were in whites, 38% in blacks, 38% in blacks, 20% in Hispanics, 20% in Hispanics, <1% in Asians and Pacific Islanders, <1% in Asians and Pacific Islanders, and <1% in American Indians and Alaska Natives;and <1% in American Indians and Alaska Natives; 46% were in men who have sex with men (MSM), 46% were in men who have sex with men (MSM), 25% in injecting drug users, 25% in injecting drug users, 11% in persons infected heterosexually, and 1% in persons 11% in persons infected heterosexually, and 1% in persons infected through blood or blood products.infected through blood or blood products.Table 25. Estimated adult/adolescent AIDS incidence, by region of residence and year of diagnosis, United StatesRegion of residence Year1996 1997 1998 1999 2000 2001Northeast 18,474 14,585 11,755 11,884 12,256 11,336Midwest 5,973 4,784 3,966 3,911 3,940 4,011South 23,620 20,058 18,318 17,233 16,844 18,364West 10,685 8,479 7,316 6,815 6,451 6,199U.S. dependencies, possessions, and associated nations2,053 1,740 1,477 1,323 1,274 1,401Total 60,805 49,646 42,832 41,165 40,766 41,311In Seattle:6,987 Adults/adolescents Living with AIDS 19 Children <13 years old7,006 total285 new cases reported in 2001348 new cases reported in 2002 HIV buds outof