Lecture 22Outline of Last Lecture I. Electrophilic Addition of Br and Cl to AlkynesII. Addition of Hydrogen Halide to AlkynesCHEM 333 1st EditionIII. Anti Makovnikov Addition of Hydrogen Bromie to AlkynesIV. Synthesis ExampleOutline of Current LectureI. Br2 or Cl2 with alkyneII. Excess Br2 with alkyneIII. Addition of HX across a triple bondIV. Hydration of Alkynes to Aldehyde or Ketonea. Hydrboration/Oxidationb. Acid Catalyzed HydrationCurrent LectureI. Br2 or Cl2 with alkyne: anti addition of Br across an alkyneII. Excess Br2 with alkyneIII. Addition of HX across a triple bonda. Mechanism:IV. Hydration of Alkynes to Aldehyde or Ketonea. Hydrboration/Oxidationi. Internal alkynes give ketones1. Example:2. Example:ii. Terminal alkynes give aldehydes1. Example:2. Example:iii. Unsymmetrical alkynes1. Example:2. Example:b. Acid Catalyzed Hydration: Markovnikov addition of carbonyli. Example:ii.
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