Welcome to Chem 36 Organic Chem Lab Dr Katie Masters Chem 36 Info Section 101 Section 102 Section 103 Monday Wednesday Tuesday Thursday Tuesday Thursday 1 25 4 25 pm 1 25 4 25 pm 6 30 9 30 pm Faculty in Charge Dr Katie Masters Director Organic Labs 218 Whitmore Lab Phone 863 3319 kmasters psu edu Dr Jackie Bortiatynski Director Instrumentation 211D Whitmore Lab Phone 865 2772 jackie chem psu edu Office Hours Wednesday 10 00 am 12 00 pm Website http courses chem psu edu chem36 Required Materials Lab Guide for Chemistry 35 Chemistry 36 Introductory Organic Laboratory Minard Masters Halmi Williamson 2005 2006 Edition Hayden McNeil Organic Chemistry Laboratory Notebook 1st Edition R Minard Hayden McNeil Eye Protection Eye Protection is required at all times in lab Organic Lab Equipment Kit Combination or key lock Lab apron and rubber gloves optional Lab Assignments First Half of Semester Second Half of Semester 5 Technique Experiments Recrystallization Melting Point Distillation Boiling Point Liquid Liquid Extraction Thin Layer Chromatography TLC Column Chromatography 5 Synthetic Experiments Assigned experiments Download from the course website Assessment Throughout the Semester Spectral Unknown Experiment Determine an unknown s structure PreLabs 30 pts and Final Reports 100 pts For each experiment you run Ch 10 has no PreLab Lab Quizzes 50 pts Quizzes 1 6 Final Exam 100 pts The Lab Experiments Chapter 4 Recrystallization and Melting Point Recrystallization MP of an Unknown Recrystallization of Phthalic Acid MP of Spectral Unknown Ch 10 experiment Decolorization with Norit Chapter 5 Distillation BP Simple or Fractional Distillation of a Known Mixture Microscale Fractional Distillation of an Unknown Mixture Chapter 6 Liquid Liquid Extraction Separation of a Solid Mixture acid base chemistry Extraction of Caffeine from Tea The Experiments Chapter 7 Thin Layer Chromatography Finding a TLC Mobile Phase Identifying Compounds in an Analgesic Tablet Chapter 8 Column Chromatography Oxidation of Fluorene to Fluorenone Column Chromatography of Reaction Mixture Chapter 9 The Synthetic Experiments 5 Synthetic Experiments downloaded from web Chapter 10 Spectral Unknown Experiment Acquire mp IR and 1H NMR spectra Determine the structure of an unknown PreLab Assignments Purpose of PreLabs Lab Quizzes To ensure that each student has read through and understands the theory and procedures of each experiment Revised PreLab Format 4 Sections 1 Purpose of Experiment 2 Diagrams of Special Apparatus Reactions 3 Chemical Data Table 4 PreLab Exercise PreLabs are hand written into the Lab Notebook White pages are handed in for grading The yellow copies are kept within the notebook NOTE You are no longer required to do Procedure Outlines Download new PreLab grade sheets from website PreLab Sections Purpose of Experiment A concise brief statement one to two sentences that describes the purpose of the experiment Never use the first person Do not include set up of apparatus in this section Good Example To sublime purify an unknown solid and to take a melting point of the purified unknown to determine its identity Bad Example I will take a melting point PreLab Sections Diagrams of Special Apparatus and or Reaction Equations Diagrams of Special Apparatus Hand draw and label any piece of glassware equipment or reaction set up that has not been used in previous experiments Please draw neatly Reaction Equations You will start including reaction equations with Chapter 8 Indicate limiting reagent and include the theoretical yield of the product PreLab Sections Chemical Data Table 1 Common Shelf Chemical Data Table Located in notebook Fill out completely and hand in with Chapter 5 PreLab 2 Blank Chemical Data Tables Located in notebook Include chemicals for the experiment that do not appear on Common Shelf Chemical Data Table Fill out all information about each chemical see example in Ch 3 Waste disposal information can be found in chapter 2 of the lab guide Use the Aldrich Catalog to find information about chemicals When using Aldrich pick the chemical entry that does NOT have isotopic labeling e g d 15N 13C These are more expensive and will have different FWs Aldrich will also tell you if a chemical is flammable or toxic or an irritant Typically use the last entry that gives all necessary data for the table Use the least pure entry for the price PreLab Sections PreLab Exercise Answer the three assigned questions located in the lab guide Assignment sheet is handed out during check in Lab Quizzes Purpose To test your understanding of theory and your preparedness for the experiments Quiz Quiz Quiz Quiz Quiz Quiz 1 Chapter 4 2 Chapter 5 3 Chapter 6 4 Chapter 7 5 Chapter 8 6 Chapter 9 and spectroscopy spectral interpretation Ch 10 11 Please note schedule for dates of quizzes They will be given at the beginning of lab and will take 10 15 minutes to complete Each are worth 50 points Graded quizzes are not allowed to leave the lab Quizzes 1 5 will include questions on the specific procedures of the chapters experiments Final Report Assignments 5 Sections I II III IV V Introduction Procedure and Data Observations Results Discussion Conclusions PostLab Exercise Reference Attach the white in lab notebook pages You must have your TA initial all pages used during each lab session Attach annotated spectral data when appropriate Attach grade sheet to the front Final reports are computer generated Reaction schemes can be hand drawn Graded final reports cannot be taken out of the lab except Ch 4 Final Report Sections Introduction First part Theory significance of technique reaction or compound Second part Brief concise description of experiment Mention techniques or analyses used Mention the name s of compound s starting material or product Do NOT include procedural detail Final Report Sections Procedure and Data Observations Paragraph format Use your in lab notebook pages carbonless copy pages to write this section Type up the procedure and include data and observations when appropriate Final Report Sections Results Discussion Conclusion 1 Presentation of results Calculations yield Rf values etc Highlight data 2 Discussion of results Evaluate the results Compare your results to expected results Talk about spectral data if applicable 3 Conclusions Comment on the success of the experiment Make suggestions for improvements or future studies Final Report Sections Reference Referencing the Lab Guide Minard B Masters K M Halmi T O