LS4-1 – GENETICS – Fall 2008Lecture: MWF 12:00-12:50pm (FOWLER A103B)Instructor:Andrew [email protected] hours: Wednesday, 1-3pmOffice: Life Science Building 4227Phone: 267-4832Teaching Assistants:Stephanie Cole Section 1D, Tuesdays, 10am-11:[email protected] Section 1F, Tuesdays, 2pm-3:50pmOffice hours: Thursday, 10am-noon Office: Life Science Building 4226 Eddie Garcia Section 1C, Mondays, 2pm-3:50pm [email protected] Section 1E, Tuesdays, noon-1:50pmOffice hours: Monday, 1-2pm; Wednesday 11am-noon Office: Young Hall 1336Michael Yourshaw Section 1A, Mondays, 10am-11:50am [email protected] Section 1B, Mondays, 4pm-5:50pm Office hours: Friday, 4-6pm Office: Gonda Building 5303 (if not there, 5554)Course material(Required) Genetics, Analysis of Genes and Genomes, 6th edition (2005)Daniel L. Hartl and Elizabeth W. Jones(Recommended) Interactive Genetics CD, (available from the student store)Assignments (See the Assignments table for weekly assignments.)Textbook: The assigned end-of-chapter problems are critical to learning the subjectmatter. You must complete the week's problems before discussion section of thefollowing week. The discussion quiz comes from among the previous week's problemsalmost verbatim.Interactive Genetics (CD): The workbook and interactive problems are anintroduction to concepts and problem solving (before starting textbook assignments).Course web site: http://www.lsic.ucla.edu/classes/fall08/On the course website you will find a copy of the syllabus, additional practiceLS4-1 Syllabus Fall 08 http://docs.google.com/View?docID=dct2f6ws_0dd694gc5&rev...1 of 3 1/16/09 9:43 AMproblems, practice midterms, keys to exams, suggested reading and more. Eachlecture will be Bruincast, which can be accessed from the course web site. Also,lecture slides will be posted in advance for use in taking notes during lecture. Onlineaccess to lectures should be treated as a supplement. Regular attendance to lecture isrequired to stay up to date on the material.GradingPoint distribution: 1st midterm exam 150 points2nd midterm exam 150 pointsfinal exam 250 pointsdiscussion section* 120 pointstotal 670 points*see Discussion sectionFinal grades: For consistency among LS4 offerings, final grades will reflect studentpercentile ranking as proscribed by the grading policy of the Life Science Core. Yourfinal grade will be based on the number of students who completed the 1st midterm.Thus, your final grade will be unaffected by the number of students who drop LS4-1after the 1st midterm. Please refrain from asking more specific questions about finalgrades.Discussion sectionYour participation in discussion section is required. This is a time to go over concepts,ask questions and do in-class assignments. You must attend the section that you areenrolled in. You need permission from the Life Science Core office to change yoursection time.There will be seven quizzes during the quarter. Each quiz is worth 20 points and isgiven 15 minutes before the end of your discussion section. A total of the six highestquiz scores will be your discussion score.Discussion sections will not meet in week 7 --Tuesday, November 11 is Veterans Dayholiday.MidtermsTwo midterms are given from 5-6:50pm on Thursday October 23rd and November13th. No make-up exams are given. If you have a conflict with scheduled exam times,please contact me as soon as possible.Returning exams: Midterm exams will be distributed during your discussion sectionthe first and second week following the exam, after which exams can be retrievedfrom the Life Science Core office.Regrading policy: If you feel a grading error was made on your midterm exam, pleasesubmit your exam to the Life Science Core office (LS 2305) no later than Friday of theweek following the exam. Attach a separate sheet with the problem number to bereviewed. Only an error that is related to the specified problem number will beconsidered.LS4-1 Syllabus Fall 08 http://docs.google.com/View?docID=dct2f6ws_0dd694gc5&rev...2 of 3 1/16/09 9:43 AMLife Science Core officeFor administrative problems related to this course, please see Lily Yanez or MarkKatayama in the Life Science Core office in LS 2305 or call them at 825-6614. Theycan assist you with scheduling difficulties or other matters related to Life ScienceCore classes.You are welcome to drop by my office to ask questions. I am not always there, andsometimes I may not have time right then, but we can arrange a more convenienttime.LS4-1 Syllabus Fall 08 http://docs.google.com/View?docID=dct2f6ws_0dd694gc5&rev...3 of 3 1/16/09 9:43 AMLS4-1 Fall 08 SyllabusLecture Schedule Assignment ScheduleWk.DateLect.TopicTextbook (Chapter.Section)0FSept. 261Introduction–1MSept. 292Molecular Markers1.7, 1.8, 2.1-2.61WOct. 13Mendelian Genetics3.1-3.31FOct. 34Gene interactions3.62MOct. 65Dominance3.62WOct. 86Probabilities3.5, 4.52FOct. 107Pedigrees3.43MOct. 138Population Genetics17.23WOct. 159DNA Testingsee website3FOct. 1710Mutation1.6, 14.1, 14.2, 14.4 14.74MOct. 2011Mitosis/Meiosis4.1-4.34ThOct. 231st EXAM (Lect. 1-10)4FOct. 2412X-linkage4.45MOct. 2713Linkage5.15WOct. 2914Genetic Maps5.25FOct. 3115Positional Cloning5.36MNov. 316Transposons14.36WNov. 517Ploidy8.1, 8.2, 8.76FNov. 718Rearrangements8.3-8.67MNov. 1019Fungal Genetics5.5, 11.5, see website7ThNov. 132nd EXAM (Lect. 11-18)7FNov. 1420Biochemical Pathways1.4, 1.5LS4-1 Fall 08 Syllabus - Google Docs http://spreadsheets.google.com/pub?key=p1NuSaY5vQrTG-K...1 of 2 1/16/09 9:45 AMEdit this page (if you have permission) – Published by Google Docs – Updated automatically every 5 minutes8MNov. 1721Bacterial Genetics9.1-9.38WNov. 1922Conjugation9.48FNov. 2123Transduction9.59MNov. 2424Phage Genetics9.69WNov. 2625Genetic Screenssee website9FNov. 28THANKSGIVING HOLIDAY10MDec. 126Organellar Inheritance16.1-16.510WDec. 327Epigenetic Inheritance11.6, 11.710FDec. 528Wrap-up–11MDec. 8Final EXAM 6:30-9:30pmLS4-1 Fall 08 Syllabus - Google Docs http://spreadsheets.google.com/pub?key=p1NuSaY5vQrTG-K...2 of 2 1/16/09 9:45 AMLS4-1 Fall 08 SyllabusLecture Schedule Assignment ScheduleWkDateQuizAssignments0Sept. 26––Sept. 29Mendelian Genetics1–Chapter 3: 1-3, 11, 12, 19-22, 29Oct. 3Interactive Genetics: Mendelian ProblemsOct. 6Pedigrees21Chapter 3: 4-10, 13-18,