1993 John Edsall (1902-2002), Physical biochemist and professor emeritus at Harvard University, member of the National Academy of Sciences, and author of several articles on the history of biochemistry and the study of hemoglobin. 1994 Shiela Tobias, Sociologist and university administrator, nationally known scholar and author of several widely acclaimed books on reforming science and mathematics education. 1994 Todd Savitt, Medical historian at East Carolina University School of Medicine, who tracked down the identity and medical history of the first two reported patients with sickle cell anemia. 1995 Vernon Ingram (1924-2006), Professor of Biology at the Massachusetts Institute of Technology and author of two of the articles in our course reader, visited this class. Dr. Ingram's classic articles reported the very first chemical characterization of a structural change in a protein (hemoglobin) associated with a genetic disease (sickle cell anemia). 1996 Anne Riley, M.D., Physician at the Alfred I. DuPont Hospital whose patients include children who have sickle cell disease. 1996 Michael Cox, Professor of Biochemistry, University of Wisconsin and coauthor of a major biochemistry textbook used in CHEM-641, 642, and 643. 1997 Rosemary Dews, Director of the Delaware Sickle Cell Foundation and two patients who had Sickle Cell Disease. 1998 Ross Hardison, Professor of Biochemistry and Molecular Biology, Penn State University, who studies the regulation of hemoglobin gene expression. 1999 Thomas G. Spiro, Professor of Chemistry, Princeton University, who studies CO binding to the iron in heme proteins. 2000 John Jungck, Chair of Biology, Beloit College, Director of the BioQuest Curriculum Consortium. 2000 Sheldon McBee, Graduate student with a family history of sickle cell disease. 2001 John Wriston (1926-2004), University of Delaware faculty member who, as a graduate student, worked with David Shemin on Heme biosynthesis. 2002 John Wright, Professor of Chemistry, University of Wisconsin. 2003 Dr. Kwaku Ohene-Frempong M.D., Director of the Comprehensive Sickle Cell Center at the Children's Hospital of Philadelphia 2003 Frank Ferrone, Professor of Biophysics at Drexel University, who studies hemoglobin S polymerization. 2003 Anthony Allison, M.D., Author of the classic article, studied in the course, that demonstrates malaria resistance among human2004 Lois W. Dow, M.D., Local retired hematologist who helped isolate human hemoglobin mRNA and knew Lemuel Diggs.2005 Jumy Fadugba, former tutor-facilitator in the course who described her recent experience with malaria.2006 Howard Dintzis, Professor Emeritis, Johns Hopkins University, Author of a classic article, studied in the course that determined the direction of protein synthesis.2007 Penny Gilmer, Florida State University biochemist and science educator.2008 Eric Mazur, Harvard University, Physics Professor and nationally known for work in active learning in lectures.CHEM-342 INTRODUCTION TO BIOCHEMISTRY SYLLABUS - SPRING 2009 On-line at: http://www.udel.edu/chem/white/C342/342-SyllabusS08.html Table of Contents Administrative Information About the Instructor …….…….……………………………….……………………page 1 Meeting Time and Place ...……………………………………..………………………...2 Prerequisites ……………………………………………………..………………………..2 Course Reader and Text ……………………………………...………………………2 Classroom Resources …………………………………………...………………………...2 Grading ……………………………………………….……...…………………………...2 Important General Information Brief Course Description …………………………………………..……………………..2 Course Objectives and Content …………………………………..………………………3 Pedagogy and Philosophy of PBL ………………………………..………………………4 Group Formation and Function …………………………………..………………………5 Tutor-Facilitators …………………………………………………..……………………..6 Assignments Reading Assignments …………………………………………………………………….7 Writing Assignments …………………………………………………………………….7 Academic Honesty…………………………………………………………………….…..8 Examinations …………………………………………………………………………….8 Course Evaluation ………………………………………………………………………..8 Distinguished Visitors ……………………………………………………….……………9 Administrative Information Instructor: Prof. Harold B. White Office: 203 Brown Lab Phone: 831-2908 (w), 737-7988 (h) E-mail: halwhite[at]udel[dot]edu Office Hours: Normally, the hour after class will be available for office hours; however, you should feel free to contact me by phone or e-mail or to stop by my office at other times. If I do not have pressing business, I will be happy to meet on the spur of the moment. Please note that I do not do e-mail at home, so messages sent in the evening or on weekends likely will not be answered until the next working day.CHEM-342 Syllabus Spring 2009 Page 2 Meeting Time and Place: 8:00 - 8:50 AM, MWF in 205 Brown Laboratory. Normally, important announcements are made at the beginning of class, so don't be late. Similarly, homework is due at the beginning of class. The tentative course schedule is available on line and will be updated regularly as necessary through the semester. Prerequisite: CHEM-331 or CHEM-321, Organic Chemistry or equivalent. Completion of or concurrent registration in introductory biology, physics, and calculus courses is assumed. Course Reader and Texts: The Course Reader, which contains photocopied articles not available on-line, is required. It and a three-ring, loose-leaf binder to contain it can be purchased at the University Bookstore. The textbook required for CHEM-641 is highly recommended as a resource. All students should have and use a good collegiate dictionary. In addition, textbooks from introductory/prerequisite biology, chemistry, physics, and math