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Reading ListBICH 407 Classic PapersSpring 2003Thursday, January 23Pauling, L., Corey, R.B., and Branson, H.R. (1951) The structure of proteins: twohydrogen-bonded helical configurations of the polypeptide chain. Proc. Natl. Acad. Sci.USA 37:205-211.Thursday, January 30Kendrew, J.C., Bodo, G., Dintzis, H.M., Parrish, R.G., Wyckoff, H., and Phillips, D.C.(1958) A three-dimensional model of the myoglobin molecule obtained by x-rayanalysis. Nature 181:662-666.Thursday, February 6Epstein, C.J., Goldberger, R.F., and Anfinsen, C.B. (1963) The genetic control of tertiaryprotein structure: Studies with model systems. Cold Spring Harbor Symp. Quant. Biol.28:439-449.(optional review article to accompany main paper - Anfinsen, C.B. (1973) Principles thatgovern the folding of protein chains. Science 181:223-230.)Thursday, February 13Watson, J.D. and Crick, F.H.C. (1953) Molecular structure of nucleic acids. A structurefor deoxyribose nucleic acid. Nature 171:737-738.Wilkins, M.H.F., Stokes, A.R., and Wilson, H.R. (1953) Molecular structure of nucleicacids. Molecular structure of deoxypentose nucleic acids. Nature 171:738-740.Franklin, R.E. and Gosling, R.G. (1953) Molecular structure of nucleic acids. Molecularconfiguration in sodium thymonucleate. Nature 171:740-741.Watson, J.D. and Crick, F.H.C. (1953) Genetical implications of the structure ofdeoxyribonucleic acid. Nature 171:964-967.Thursday, February 20Lehman, I.R., Bessman, M.J., Simms, E.S., and Kornberg, A. (1958) Enzymatic synthesisof deoxyribonucleic acid. I. Preparation of substrates and partial purification of anenzyme from Escherichia coli. J. Biol. Chem. 233:163-170.Thursday, February 27Meselson, M. and Stahl, F.W. (1958) The replication of DNA in Escherichia coli. Proc.Natl. Acad. Sci. USA 44:671-682.Thursday, March 6Brenner, S., Jacob, F., and Meselson, M. (1961) An unstable intermediate carryinginformation from genes to ribosomes for protein synthesis. Nature 190:576-581.Leder, P. and Nirenberg, M. (1964) RNA codewords and protein synthesis, II.Nucleotide sequence of a valine RNA codeword. Proc. Natl Acad. Sci. USA 52:420-427.Thursday, March 20Hall, B.D. and Spiegelman, S. (1961) Sequence complementarity of T2 DNA and T2-specific RNA. Proc. Natl. Acad. Sci. USA 47:137-146.Thursday, March 27Cohen, S., Chang, A., Boyer, H., and Helling, R. (1973) Construction of biologicallyfunctional bacterial plasmids in vitro. Proc. Natl. Acad. Sci. USA 70:3240-3244.Thursday, April 3Maniatis, T., Hardison, R.C., Lacy, E., Lauer, J., O’Connell, C., Quon, D., Sim, G.K., andEfstratiadis (1978) The isolation of structural genes from libraries of eucaryotic DNA.Cell 15:687-701.Thursday, April 10Berget, S.M., Moore, C., and Sharp, P.A. (1977) Spliced segments at the 5’ terminus ofadenovirus 2 late mRNA. Proc. Natl. Acad. Sci. USA 74:3171-3175.Thursday, April 17Kruger, K., Grabowski, P.J., Zaug, A.J., Sands, J., Gottschling, D.E., and Cech, T.R. (1982)Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA interveningsequence of Tetrahymena. Cell 31:147-157.Thursday, April 24Saiki, R.K., Gelfand, D.H., Stoffel, S., Scharf, S.J., Higuchi, R., Horn, G.T., Mullis, K.B.,and Erlich, H.A. (1988) Primer-directed enzymatic amplification of DNA with athermostable DNA polymerase. Science


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