U-M BIOMEDE 419 - Vascular Biology I - Components of the Vascular System (7 pages)

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Vascular Biology I - Components of the Vascular System



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Vascular Biology I - Components of the Vascular System

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Pages:
7
School:
University of Michigan
Course:
Biomede 419 - Quant Physiology
Quant Physiology Documents

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BME 419 519 Hernandez 2002 Vascular Biology I Components of the Vascular System Functions of Vascular system 1 Active transport of substances through the body small organisms have mostly passive transport Nutrients glucose ATP Oxygen waste hormones chemical signals host defenses WBC platelets globulins etc 2 Regulation of that flow Arterial shunts to distribute blood flow to organs that need it the most eg blood flow to the brain and heart must be maintained at all costs so in the event of blood loss vasoconstriction occurs Basal tone tonic contraction of vessel smooth muscle in the absence of external stimulation 3 Thermal regulation Blood flow through skin heat radiation cooling quite efficient By redirecting flow you can cool down or heat up internal organs maintenance of homeostasis BME 419 519 Organ Brain Heart Skel Musc Skin Kidney Abd Organs Other Total Hernandez 2002 Distribution of systematic blood flow Flow Rate of Total Flow Rate with at Rest Flow Strenuous Exercise ml min ml min 650 13 750 215 4 750 1 030 20 12 500 430 9 1 900 950 20 600 1 200 24 600 545 10 400 5 000 100 17 500 of Total Flow 4 4 73 11 3 3 2 100 Components of the Cardiovascular System 1 Heart obviously the pump that drives the system more details elsewhere 2 Blood main components a Erythocytes Red Blood Cells Carry oxygen bound to hemoglobin molecules Hematocrit of blood volume made up by erythrocytes b Leukocytes White Blood Cels bind engulf and digest debris c Plasma the solvent Contains mostly water proteins dissolved gasses nutrients hormones waste products d Platelets Responsible for clotting repair of damaged tissue plug for hemorrhages The clotting process consists of a complex cascade of chemical signals 3 Lymphatic system endothelial filtration can produce excess water and other materials mostly protein lymph Parallel vascular system that returns this fluid into the veinous system at the junctions of subclavian and jugular veins Flow is passive powered by muscle contractions and



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