LS4 INTRODUCTORY GENETICS WINTER QUARTER, 2011 LECTURE: Tuesday, Thursday 12:30-1:50 PM in LaKretz 110. INSTRUCTOR: Frank Laski, 5018 Terasaki Life Sciences Bldg. TEACHING ASSISTANTS: Patrick Aghajanian, Jennifer Chun, Ron Siu and Jon Voutila. TEXT: Genetics, from Genes to Genomes , 3rd or 4th Edition, Hartwell et. al. Optional: Study Guide/Solutions Manual with detailed problem solutions. COMPACT DISC: Interactive Genetics, CD-ROM and workbook. # Date & Day TOPICS READINGS; 4th ED. 1 1/4 Tu Introduction, Mendel Ch. 1, 2 2 1/6 Th Pedigree Analysis & Extensions on Mendel Ch. 3 3 1/11 Tu Mitosis & Meiosis; Ch. 4 4 1/13 Th Chromosome theory of inheritance and Sex Determination 5 1/18 Tu Linkage and Recombination Ch. 5 (pp 118-135) 1/18 Tu MIDTERM #1 5-6:50 PM (covering lectures 1-4) 6 1/20 Th One Gene-One Enzyme Ch. 7 (pp 224-226) 7 1/25 Tu Bacterial Genetics Ch. 14 (477-482) 8 1/27 Th Bacteriophage Genetics, Life cycle, recombination Ch. 14 (486-494) 9 2/1 Tu Bacteriophage Genetics, Lysogeny, 10 2/3 Th Benzer and the rII locus Ch. 7 (pp 216-224) 2/7 M MIDTERM #2 5-6:50 PM (covering lectures 5-10) 11 2/8 Tu Transcription, translation, DNA Function, Ch. 8 (pp 246-272) 12 2/10 Th Crick experiment (triplet codon) Ch. 8 (pp 276-281) 13 2/15 Tu Genetic control in prokaryotes; lac operon Ch. 15 (pp 519-528) 14 2/17 Th Recombinant DNA Ch. 9 (290-317) 15 2/22 Tu Molecular Genetics TBA 16 2/24 Th Population Genetics; Hardy Weinberg; Ch. 19 (pp 655-660; 665-668) 2/28 M MIDTERM #3 5-6:50 PM (covering lectures 11-16) 17 3/1 Tu Human Genetics TBA 18 3/3 Th Human Genetics 19 3/8 Tu Human Genetics 20 3/10 Th Human Genetics 3/18 F FINAL 11:30 AM-2:30 PM (covering entire class) The Life Sciences Core Office: For any administrative and scheduling problems relating to this course, please go to the Life Sciences Core Office in Life Sci. Bldg., room 2305, 825-6614. [email protected] Exams: Genetic problems and short essays. Questions will be drawn from the lectures and assigned problems. The reading assignments are to help you understand the lectures and problems. Exams will be closed book, except you are allowed a single 8½ x 11 inch piece of paper that can contain written notes on both sides of the paper (a legal cheat sheet). The paper should have your name written in 1-inch tall letters at the top of both sides. You cannot pass this paper to another student during an exam.Turning Point Clickers: Students are required to bring Turning Point clickers to class. Students use clickers to respond to questions posed during lecture. Answering questions for each lecture is worth 1 point. Follow the instructions in the Blackboard announcement (and e-mailed to you) to register your clicker. You must answer the questions each day to receive the participation credit for that day. Please do not attend the lecture if you do not feel well, you will receive four “free days” of points – this means that you can miss four lectures and not be penalized points. Course Grading: 100 points for each Midterm; 200 points for the final. Your lowest 100 points from an exam will be dropped. 20 points for clicker question participation. Grades will be based on a curve of 420 total points. Regrading Policy: Any request for regrade must be made within one week of the exam being returned to you. If you think there is an error in grading, you must submit a written explanation of why you think it was graded incorrectly. Turn in these requests to the Core Office with your entire exam. You should photocopy your exam before you hand it in. Regrade requests are only considered at the end of the quarter, and only if the points in question will affect your final letter grade in the course. Oral arguments will not be considered. If you ask for a regrade, the entire test may be regraded and your score may move up or down. Sections: Sections will meet in the computer room, 1054 Young Hall. Please attend the section you are assigned to. Clinics: Dr. Laski will hold an optional clinic for instruction in solving genetic problems and answering genetic questions. It will be held on most Fridays from 3:00 PM to 4:30 PM in LaKretz 110. A weekly announcement will inform you whether the clinic will be held. Office hours: Dr. Laski’s office hours are Tuesdays, 2:30-4:00PM in 5018 or 5100 Terasaki Life Sciences Bldg. Bruincast replays of lectures can be found at www.bruincast.ucla.edu If you have access problems, please contact Bruincast at: