GradingChem/Biol 473 Biochemistry Spring 2006Instructors: G. Prody K. Cude Office: CB 444 BI 447A Phone: 650-3156 650-6220 Office hours: M TR 12-1 pm TR 11 am-12:30 pm or by appointment. e-mail: [email protected] [email protected]: MWF 11, CB 285Texts: Voet and Voet, Biochemistry 3rd edition (2004). Wiley & Sons, Inc. Alberts et.al, Molecular Biology of the Cell 4th edition (2005) Garland ScienceWe will also be posting additional reading assignments from journals Exams: 2 evening midterm exams @ 100 points. Exams will be given from 6-8 pm. Clear your schedules NOW!!!!!!!!!!!!!Wednesday April 19Wednesday May 10 1 cumulative final @ 200 points Monday June 5, 10:30 am-12:30 pmGradingYour grade will be determined from the sum of your exam scores plus points you receive for class participation as follows: Each student will fill out an index card with pertinent information.During class, I (GP) will call on students to answer questions by drawing a card. You will receiveone + for being present and another for providing a correct response. Lifelines are available. At the end of the quarter, we will normalize your +/- values and determine your total out of 50 possible points. The class average for the CUMULATIVE total point sum will be a B-.Course content: This quarter we will concentrate mainly on molecular biology and we hope you will be as excitedas we are about the course content. Knowledge in this field is being accumulated at an incredible rate. We make every attempt to keep current, but the field changes so rapidly that occasionally we miss something. Please be sure to read ahead in your texts, as this will help you understand the lecture material (We'll let you know if your texts are out of date in spots). We will be covering an incredible amount of material this quarter and even at that, will only be scratching the surface of the information available on these topics. It is imperative that you keepup with the reading. We look forward to your participation in class discussions. As usual, the exams will consist mostly of problems related to the material covered. "Practice makes perfect!"In addition, we encourage you to attend as many chemistry and biology seminars as possible. The Chemistry seminars are held Fridays at 3:30 pm in CB 285. Biology seminars are Wednesdays at 4 pm in BI 212. NB: The seminar on W 4/12 will be given by Dr. Cude.Chem/Biol 471, Fall 2004Tentative Lecture ScheduleSubject to CHANGE!Reading Suggestions: Those in italics refer to Alberts. Those in bold refer to Voet.Week Monday Wednesday Friday#1 no class Intro to Course TranscriptionMar 27-31 Ch 5, 29 (GP) Ch 31 (GP)#2 RNA processing (I) RNA processing (II) Translation Apr 3-7 GP GP Ch 32 (GP)#3 DNA binding proteins Regulation/OperonsRegulation of Cell ProcessesApr 10-14 (GP) (GP)Chp 3,15 (KC)#4 Introduction to Cell Cycle Review Cell Cycle in DepthApr 17-21Chp 17 (KC)*Evening EXAM 1*Chp 15-18 (KC)#5 Cell Cycle in Depth Cell Cycle in Depth Cell Cycle in DepthApr 24-28Chp 15-18 (KC) Chp 15-18 (KC) Chp 15-18 (KC)#6 Checkpoints Immunity (I) Immunity (II)May 1-5Chp 17 (KC)Ch 35 (GP) (GP)# 7 Immune (III) Review HIV (I)May 8-12 (GP) *Evening EXAM 2* (GP)# 8 HIV (II) Flu Cancer May 14-19 (GP) Ch 33 (GP)Chp 23 (KC)#9 Cancer DNA damage repair DNA damage repairMay 22-26Chp 23 (KC) Chp 5 (KC) Chp 5 (KC)#10 Memorial Day Apoptosis Apoptosis/AgingMay 29-Jun2 HolidayChp 17 (KC) Chp 17