2.79J/3.96J/20.441J/HST522J Biomaterials - Tissue Interactions Homework #3 1. Write 3 unit cell processes that could occur in the acute phase of wound healing of a vascularized tissue, showing their interactions. 2. Write 2 unit cell processes that could occur during the chronic phase of wound healing, showing their interactions. 3. A major problem with joint replacement prostheses is polyethylene particle-induced degradation of bone (referred to as "osteolysis"; see Fig. 1). Write the unit cell process(es) to describe this phenomenon. Name possible regulators when they are known.Fig. 1. Article from the Pittsburgh Post Gazette showing the particles of polyethylene, generated by awear process, infiltrating the tissue around a prosthesis. The area shown as “weakened bone” is a region where bone resorption has resulted from the response to the polyethylene particles. Figure by MIT OpenCourseWare. Sources: University of Pittsburgh and Pittsburgh Post Gazette.MIT OpenCourseWarehttp://ocw.mit.edu 20.441J / 2.79J / 3.96J / HST.522J Biomaterials-Tissue Interactions Fall 2009 For information about citing these materials or our Terms of Use, visit:
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