WFSC 403 6th Edition Lecture 19 Outline of Last Lecture I Chapter 13 Disease and Parasitism a Not on Wednesday test II Basic concepts and definitions a Link to predation and competition III Math modeling of host disease interactions IV E C S P H C 2C a Trophic food chain Outline of Current Lecture I Basic Concepts a Review b One Health prudent predator Virulence RQ SEIR i Rabies fig 13 14 page 246 II Math Models of host disease a General model i Fig 13 1 p 236 b SIR closed population c SI open population d R0 working with data i Page 237 e Disease control vaccines cull i Page 238 Current Lecture Difference between what disease and parasites do to host o Macro disease agents reproduce in host These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute o Parasites do not reproduce in the host They do not complete life cycle in host What is virulence o Intensity of the disease Often measured by death rate RQ is Red Queen Prudent Predator o Don t want to gobble up all the prey because then you will starve to death What does the RQ PP and Virulence have in common o Pathogens should evolve to be more benign Don t want to kill host before you have time to spread Host develops mechanisms to combat the virulence Arms race between host and pathogen prevents virulence from getting out of control RQ is run and run just to stay where you are One Health o Integrate human and veterinary medicine o Pathogens are common and passed between each They are circulating in the environment so these should be incorporated as well SIR o Susceptible Incubating Infectious Recover I is also E for exposed o SIR model Closed population no births and deaths Working with data Page 237 Read through this B R 0 Run out of susceptible in a closed model Could run out of infectious Replenish of susceptible when babies are born in a population N is number of population o bN dX bN assumes that the disease does not affect birth rate o d Y is additional mortality from disease the infected Bottom 238 o How many must be removed via culling or vaccine o What is the big picture What does it all mean Synthesize o Can calculate if there will be an epidemic o Stable cycles predator prey Don t really see that with this o Coevolution of predator prey evolution Arms race o Evolution of virulence
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